Klaus Tenbrock Selected Research

Cyclic AMP Response Element Modulator

1/2017	Hepatic overexpression of cAMP-responsive element modulator α induces a regulatory T-cell response in a murine model of chronic liver disease.
1/2016	CREM Alpha Enhances IL-21 Production in T Cells In Vivo and In Vitro.
4/2013	cAMP responsive element modulator: a critical regulator of cytokine production.
12/2012	cAMP-responsive element modulator α (CREMα) contributes to decreased Notch-1 expression in T cells from patients with active systemic lupus erythematosus (SLE).
12/2011	cAMP-responsive element modulator (CREM)α protein induces interleukin 17A expression and mediates epigenetic alterations at the interleukin-17A gene locus in patients with systemic lupus erythematosus.

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Klaus Tenbrock Research Topics

Disease

17	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2022 - 10/2002
9	Inflammation (Inflammations) 01/2022 - 01/2011
8	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 03/2021 - 02/2014
4	Hypersensitivity (Allergy) 12/2018 - 03/2007
4	Arthritis (Polyarthritis) 06/2018 - 05/2015
3	Asthma (Bronchial Asthma) 01/2020 - 11/2015
3	Autoimmune Diseases (Autoimmune Disease) 08/2014 - 11/2002
2	Hepatitis 01/2021 - 03/2015
2	Infections 01/2020 - 01/2018
2	Hypoxia (Hypoxemia) 03/2007 - 04/2003
1	Proteinuria 01/2022
1	Hypertension (High Blood Pressure) 01/2022
1	Pulmonary Arterial Hypertension 06/2021
1	Alveolar capillary dysplasia 06/2021
1	Cutaneous Lupus Erythematosus 01/2021
1	Macrophage Activation Syndrome 01/2020
1	Neonatal Sepsis 01/2020
1	Cytopenia 01/2020
1	Congenital Plasminogen Deficiency 01/2019
1	Rheumatic Diseases (Rheumatism) 01/2019
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2019
1	Drug Hypersensitivity (Drug Allergy) 12/2018
1	Body Weight (Weight, Body) 11/2018
1	Experimental Arthritis 06/2018
1	Neoplasms (Cancer) 01/2018
1	Stroke (Strokes) 04/2017
1	Liver Diseases (Liver Disease) 01/2017
1	Demyelinating Diseases (Demyelinating Disease) 03/2016
1	Colitis 01/2016
1	Negative rheumatoid factor polyarthritis 12/2015
1	Respiratory Hypersensitivity 11/2015
1	Lupus Nephritis 06/2015
1	Pneumonia (Pneumonitis) 03/2015
1	Cystic Fibrosis (Mucoviscidosis) 10/2014
1	Lung Diseases (Lung Disease) 10/2014
1	Allergic Bronchopulmonary Aspergillosis 10/2014
1	Acute Lung Injury 08/2013

Drug/Important Bio-Agent (IBA)

9	CytokinesIBA 03/2021 - 01/2011
5	Proteins (Proteins, Gene)FDA Link 01/2019 - 10/2002
5	Cyclic AMP Response Element ModulatorIBA 01/2017 - 12/2011
5	Interleukin-2 (IL2)IBA 04/2005 - 10/2002
3	Transcription Factors (Transcription Factor)IBA 06/2018 - 03/2015
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2022 - 06/2015
2	Interleukin-1 (Interleukin 1)IBA 03/2021 - 01/2020
2	Concanavalin AIBA 01/2021 - 03/2015
2	OvalbuminIBA 01/2020 - 06/2018
2	Etanercept (Enbrel)FDA Link 01/2020 - 05/2015
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 02/2014
2	SteroidsIBA 01/2020 - 12/2008
2	Toll-Like Receptor 4IBA 01/2019 - 09/2007
2	AllergensIBA 01/2017 - 03/2007
2	Interleukin-17 (Interleukin 17)IBA 01/2017 - 12/2011
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 09/2011 - 09/2004
2	zeta chain antigen T cell receptor (TCR zeta chain)IBA 11/2005 - 11/2002
2	Adenosine (Adenocard)FDA LinkGeneric 09/2004 - 10/2002
1	MicroRNAs (MicroRNA)IBA 01/2022
1	AntibodiesIBA 01/2022
1	Oxygen (Dioxygen)IBA 06/2021
1	Leucine (L-Leucine)FDA Link 04/2021
1	Cell Adhesion Molecule-1IBA 01/2021
1	Cell Adhesion MoleculesIBA 01/2021
1	IntegrinsIBA 01/2021
1	LigandsIBA 01/2021
1	AcidsIBA 01/2020
1	tocilizumab (atlizumab)FDA Link 01/2020
1	canakinumab FDA Link 01/2020
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2020
1	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2020
1	PlasminogenIBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2019
1	Methotrexate (Mexate)FDA LinkGeneric 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	Antirheumatic Agents (DMARD)IBA 01/2019
1	CalciumIBA 01/2019
1	Biological ProductsIBA 01/2019
1	AlarminsIBA 01/2019
1	Pattern Recognition ReceptorsIBA 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2018
1	InterleukinsIBA 01/2018
1	Adenosine DeaminaseIBA 04/2017
1	Immunoglobulin E (IgE)IBA 01/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2016
1	Dextrans (Dextran)FDA Link 01/2016
1	interleukin-21 (interleukin 21)IBA 01/2016
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2016
1	Interleukin-12 Subunit p40IBA 12/2015
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 06/2015
1	Mycophenolic Acid (Cellcept)FDA LinkGeneric 06/2015
1	Adenosine Monophosphate (AMP)IBA 03/2015
1	ElementsIBA 03/2015
1	Omalizumab (Xolair)FDA Link 10/2014
1	GlucocorticoidsIBA 08/2014
1	LipopolysaccharidesIBA 08/2013
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 12/2012
1	sulforaphaneIBA 10/2012
1	Phenobarbital (Luminal)FDA Link 08/2012
1	AntigensIBA 08/2012

Therapy/Procedure

7	Therapeutics 01/2021 - 08/2014
1	Artificial Respiration (Mechanical Ventilation) 06/2021
1	Biological Therapy 01/2020